The unique concept of EUNCL as a multi-competence service center offers a comprehensive and sophisticated portfolio of assay covering fields from chemical/physical to in vitro/in vivo characterization of promising nanomaterials. The tired characterization process is coordinated by a manager who also facilitates the communication with the sponsor.


Test facilityInstrumental nameProducerModel
physical chemical characterisation BET BEL Japan Belsorp Max
  DLS (Dynamic Light scattering) PCS MALVERN ZetaSizer NanoZSP
  AFM (Atomic Force Microscope) BRUKER Multimode
  SEM (Scanning Electron Microscopy) ZEISS LEO 1530
  TEM (Transmission Electron Microscopy) TECNAI OSIRIS
  FFF (Filed Flow fractionation) WYATT ECLIPSE
  EDS (Electron Dispersive X-ray Spectrocopy) BRUKER Quantax xflash 5030
  ICP-MS (Ion Coupled Plasma Mass Spectroscopy) AGILENT 7700X
  UV-VIS AS (Ultra Violet and Visible light Absorption Spectroscopy) SHIMATSU  
  FTIR (Fourier Transform Infrared Spectroscopy) RIGAKU Nanohunter
  NME ( Nuclear Magnetic Resonance) BRUKER AVANCE 200,400,500
  Pro-inflammatory cytokine detection (IL8 & TNF-alpha) BIORAD Bioplex MagPix
  Endotoxin contamination using LAL test    
  Microbial contamination using PhEur-test About to be purchased  
  Mycoplasma contamination using PhEur test    

More Informations (Website)


Test facilityInstrumental nameProducerModel
physical chemical characterisation Closed Vessel Microwave Digestion CEM Corporation Discover
  Homogenizer GEA Mechanical Equipment SpA Panda
  Disk Centrifuge Sedimentation CPS Instruments Inc. DC24000UHR
  UV/Vis Spectrophotometer Thermo Nicolet Evolution 300
  Field-Flow Fractionation Postnova Analytics AF2000 AT
  Field-Flow Fractionation Postnova Analytics PN4020
  Zeta Sizer Malvern Instruments Ltd NanoZS
  Nanoparticle Analysis System Malvern Instruments Ltd Nanosight LM20
  Nanoparticle Sizer IZon Q-Nano
  Circular Dichroism Spectrometer Jasco Corp. J-815
  Fluorescence Spectrometer Varian CARY Eclipse
  Fourier Transform Infrared Spectrometer (FT-IR) Bruker Tensor27
  Fourier Transform Infrared Spectrometer (FT-IR) Bruker Vector22
  ICP-MS Agilent Technologies 7700Series
  Atomic Force Microscope 1 NT-MDT Solver
  Atomic Force Microscope 2 Agilent Technologies AFM5500
  Surface Plasmon Resonance Imaging Horiba SPRi Plex
  Fluorescence Lifetime Spectrometer ISS inc. Chronos FD
  Ultramicrotome LEICA Cryo Leica EM VC7
  Automatic Plunge Freezing System LEICA EM GP
  X-Ray Photoelectron Spectroscopy (XPS) Kratos Analytical Ltd. AXIS Ultra
  Closed Vessel Microwave Digestion CEM Corporation Discover
  Homogenizer GEA Mechanical Equipment SpA Panda
Imaging and Microcopy Transmission Electron Microscope JEOL Ltd. JEM2100
  Scanning Electron Microscopy – Focused Ion Beam FEI NOVA600 Dual Beam
  Raman Confocal Microscope Witec Alpha300
  Fluoroscent mircoscope Zeiss Apotome+Axiovert 200
  Cell Imaging System GE Healthcare-Euroclone Incell2200
Biology and Cell culture Multiwell plate reader Perkin Elmer Enspire
  Flow Cytometer Partec CyFLOW space
  Colony counter Oxford Optronix  
  Comet Microscope Andor comet  
  Electric cell impedance Sensing applied biophysics ECIS s Z
  Lable free optical biosensor SDK biotechnologies Dynetix BR8
  Quartz Crystal Microbalance Biolin Scientific Q-Sense E4
  Imaging Nanoplasmonics Plasmore SRL Impressor 1.0

More Informations (Website)


Test facilityInstrumental nameProducerModel
in vitro toxicology Cell cultivation laboratory Several instruments. Several instruments
  Liquid handling workstation Tecan Evo2 with MCA384
  Liquid handling workstation Beckman Coulter Orca system with NXP liquid handling robot
  Flow cytometer Life technologies Attune
  Automated microscope with onstage incubator Life technologies EwosFL Auto
  Microplate reader Tecan Infinity 200Pro
  Microplate reader Beckman Coulter Paradigm
  UV/Vis Spectrophotometer, microplate reader Molecular Devices SpectraMAX384Plus
  LC and LCMS system Agilent Agilent 1200 LC with 6490 QQQ MS
  LC and LCMS system Agilent Agilent 1200 LC with 6510 QTOF MS
  General cell cultivation laboratory Several instruments… Several instruments…

More Informations (PDF, 0.5 MB)


Test facilityInstrumental nameProducerModel
In vivo toxicology Stabularium (Wistar rats (biodistribution), C57BL/6J strain mice (acute/chronic toxicity) ventilated cages (IVC system, Tecniplast, Italy)  
  Histopathology laboratory standard equipment  
  Clinical chemistry standard equipment for assessing (ALT<AST<Serum Amyloid A, BUN, Bilirubin)  

More Informations (Website)


Test facilityInstrumental nameProducerModel
immunological characterisation MACSQuant flow cytometer Miltenyi Biotec MACSQuant
  FACS Canto II Bioplex 200    
  Monochromatic plate reader with atmospheric control unit    
  automated cell separation equipment Miltenyi Biotec AutoMACS
hematological characterisation coagulometer Merlin MC4+  
physical characterisation dynamic light scattering (DLS) Malvern Instruments Ltd nanoZS
  NMR spectroscopy    
  field flow fractionation    
  isothermal titration calorimetry (ITC)    

More Informations (PDF, 0.5 MB)


Test facilityInstrumental nameProducerModel
Analytical Chemistry (EU-NCL-relevant instruments) liquid chromatography (HPLC) Bruker EVOQ Advance UHPLC
  capillary electrophoresis (CE) coupled with selective detectors including UV/vis absorbance, fluorescence and electrochemical Agilent CE and 3D CE
  Gas chromatography (GC) equipped with Multi Purpose Sampler (MPS); GC coupled with selective detectors including mass spectrometric detector, FID Agilent G 1530 A
  laser ablation (LA)-ICP-MS LA: CETAC coupled with ICP-MS: Thermo Fisher Scientific LSX-213 G2+ICAP Q ICP-MS
  micro-X-Ray Fluorescence analysis (µXRF). Bruker M4 Tornado
  ICP-MS Analytik Jena Plasmaquant-MS Elite
Tascon Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) IONTOF TOF.SIMS5
  X-ray Photoelectron Spectroscopy (XPS) PHI Quantera
  Low Energy Ion Scattering (LEIS) IONTOF q-tac 100
  White Light Interferometry/Confocal Height Measurements Sensofar Plu neox
BMTZ Cell cultivation laboratory Several instruments. Several Models
  Cell culture incubator Heraeus/Thermo Scientific HeraCell several
  Sterile work safety cabinets Heraeus/Thermo Scientific HeraSafe several
  Cell counter and analyser Schärfe System GmbH CASY TT
  Multi-point stirrer Thermo Scientific Variomag Telesystem 60
  Platewasher Dynex Technologies Opsys MW
  Modular multimode reader with advanced liquid handling BMG Labtech NOVOstar
  Fluorescence multi-mode microplate reader BMG Labtech FLUOstar Optima
  LVF Monochromator multimode reader BMG Labtech CLARIOstar
  Cryoscopic Osmometer Gonotec Osmomat 030
  DLS (Dynamic Light scattering) MALVERN Instruments ZetaSizer Nano-ZS
  Ultrasonic device Hielscher, Brandson, Bandelin Diverse models
  Concentrator Savant Instruments Speed Vac SC110
  Centrifuge Diverse models  
  Potentiometric STAT Titrator Methrom Titrando 902
  Microscopes, Fluorescence, Inverted, and diverse settings Olympus, Nikon IX-81; BX-41, IX-71, diverse
  Digital holography microscopy diverse equipment  
  Microinjection Eppendorf FemtoJet+Injetman N12
  Microtome Microm Microm HM 315
  Fluorescence Imager / Chemo Luminescence Imager Intas Science Imaging Advanced Imager
  Gel Imager Intas Science Imaging Gel iX Imager
  General molecular biology laboratory Diverse equippment Diverse models
  General protein biochemistry laboratory Diverse equippment Diverse models
  Gel Electrophoresis and gel transfer BIORAD Multiple equipment
  Sterilisation Autoclave Systec Vx-150
  In vitro cytotoxicity assays Matrix with different test methods available Up to 10 or more selected cell lines applicable for test matrix
  Endotoxin contamination LAL test LAL based assays  
  Microbial contamination test Several test methods  
  Mycoplasma contamination test Nested PCR based assay  
OxProtect Flow Cytometer Becton Dickinson Calibur
  Platelet Aggregometer Mölab GmbH PAP-4
  Cell Counter Sysmex KX-21N
  ELISA Reader Tecan Sunrise
  Coagulometer Behnk Thrombotimer-4
  2D Electrophoresis Amersham Ettan IPGphor II
Vivo Science Elisa Reader Tecan Surise
  Beta Counter Wallac Micro beta 1450
  FACS beckman coulter cytomics FC 500
  Mikrotomes Leica RM2245
  Tissue prossessing Medite TPC 15 DUO
  Embedding station Bavimed FX 13

More Informations (Website)

European Nanomedicine Characterisation Laboratory (EUNCL)

Call for Proposals!


  • Final Executive Board and CET Meeting
    The EUNCL Executive Board and CET met at MedTech Europe in Brussels to arrange the last steps before closure of the project. An important and well-prepared discussion point was the way forward to ensure that the strong collaboration of partners will lead to a successful continuation of the service offered to start-ups and companies.
  • EUNCL at CRS Annual Meeting in Valencia
    EUNCL was invited to present in Valencia, Spain at the 46th Controlled Release Society Annual Meeting & Exposition! Held in the Palacio de Congresos de València from July 21st-24th, this premier event spoted a powerful lineup of presenters including Nobel Laureates, Academic powerhouses and Industry game changers celebrating the progress in the areas of bioengineering, drug delivery, material science, pharmaceutics, consumer and diversified products, and veterinary science.
  • Last General Assembly met in Stoos, Switzerland 23. - 24. May 2019
    The project’s last General Assembly took place under the motto ‘overview, impact and forecast’. The Work Package leader presented a pre-final report on their respective WPs, recapitulating the tasks accomplished during the last 3,5 years of the project’s runtime.

More News ...